Article 5120

Title of the article

ESTIMATION OF EFFICIENCY OF GEL SORBENTS’ APPLICATION IN BLOOD ON TRAUMATIC LIVER INJURIES 

Authors

Vorontsov Aleksey Konstantinovich, Candidate of medical sciences, head of the first surgical department, Bryansk City Hospital No. 1 (11, Kamozina street, Bryansk, Russia), E-mail: ale92112855@yandex.ru
Troshin Vladislav Pavlovich, Doctor of medical sciences, professor, head of the pathological department, Bryansk City Hospital No. 1 (11, Kamozina street, Bryansk, Russia), E-mail: vptbr32@mail.ru
Parkhisenko Yuriy Aleksandrovich, Doctor of medical sciences, professor, sub-department of hospital surgery, Voronezh State Medical University named after N. N. Burdenko (10, Studencheskaya street, Voronezh, Russia), E-mail: parkhisenko46@mail.ru
Korsakov Anton Vyacheslavovich, Doctor of biological sciences, professor, sub-department of life safety and chemistry, head of Research Laboratory “Human Ecology and Data Analysis in the Technosphere”, Bryansk State Technical University (7, 50th anniversary
of October boulevard, Bryansk, Russia), E-mail: korsakov_anton@mail.ru
Klimashevich Aleksandr Vladimirovich, Doctor of medical sciences, professor, sub-department of surgery, Medical Institute, Penza State University (40, Krasnaya street, Penza, Russia), E-mail: klimashevich78@mail.ru 

Index UDK

615.035.9 

DOI

10.21685/2072-3032-2020-1-5 

Abstract

Background. Injuries resulting from traffic accidents, falls, violence or hostilities annually result in the death of more than five million people and account for 9 % of all deaths in the world. Damage to the liver is characterized by special severity, the difficulty of recognition and treatment, especially injuries that are associated with damage to large venous vessels. The aim of our study was to study the absorbent properties of widely used hemostatic drugs in an in vitro experiment.
Material and methods. The hemostatic sponge, Tachocomb, Surgitamp and Molselect were chosen as the tested sorbents. In vitro, the test materials (hemostatic sponge, Tachocomb, Molselect, Surgitamp) of the same shape and size were placed, the tubes had pre-prepared blood in the amount of 30 ml. The obtained experimental data were approximated by a fifth degree polynomial by the least squares method.
Results. It has been established that it is most effective to apply “spraying” with a layer of 2 mm, since the volume of absorbed blood is greatest. At the same time, evaluating the cost of materials under equal conditions of use, Molselect has a greater economic prospect.
Conclusions. The results show that Molselect has the highest absorbing properties compared to other drugs, which makes its use in clinical practice the most promising. 

Key words

liver injuries, hemostatic materials, gel sorbents, blood absorption, mathematical model 

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References

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Дата создания: 20.05.2020 12:42
Дата обновления: 20.05.2020 13:30